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HOME > Hospitals > Severance Hospital > Departments > Endocrinology and Metabolism > Physician Directory

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Yongho Lee
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Name Yongho Lee
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Research

Adenoviral vector-mediated glucagon-like peptide 1 gene therapy improves glucose homeostasis in Zucker diabetic fatty rats
Journal Of Gene Medicine 10/ :260-268,2008

Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population
Journal Of Human Genetics 53/ :991-998,2008

Functional expression of CXCR4 in somatotrophs: CXCL12 activates GH gene, GH production and secretion, and cellular proliferation
Journal Of Endocrinology 199/ :191-199,2008

Korean red ginseng (Panax ginseng) improves insulin sensitivity and attenuates the development of diabetes in Otsuka Long-Evans Tokushima fatty rats
Metabolism-Clinical and Experimental 58/8 :1170-1177,2009

Protective effects of magnesium lithospermate B against diabetic atherosclerosis via Nrf2-ARE-NQO1 transcriptional pathway
Atherosclerosis 211/1 :69-76,2010

Natural therapeutic magnesium lithospermate B potently protects the endothelium from hyperglycaemia-induced dysfunction
Cardiovascular Research 87/ :713-722,2010

Absence of activating mutations of CXCR4 in pituitary tumours
Clinical Endocrinology 72/2 :209-213,2010

Visceral adiposity and the severity of coronary artery disease in middle-aged subjects with normal waist circumference and its relation with lipocalin-2 and MCP-1
Atherosclerosis 213/12 :592-597,2010

The cyclic pentapeptide d-arg3FC131, a CXCR4 antagonist, induces apoptosis of somatotrope tumor and inhibits tumor growth in nude mice
ENDOCRINOLOGY 152/2 :536-544,2011

Predictive characteristics of patients achieving glycaemic control with insulin after sulfonylurea failure
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE 65/10 :1076-1084,2011

Lithospermic acid B protects beta-cells from cytokine-induced apoptosis by alleviating apoptotic pathways and activating anti-apoptotic pathways of Nrf2-HO-1 and Sirt1
TOXICOLOGY AND APPLIED PHARMACOLOGY 252/1 :47-54,2011

Glycated albumin is a useful glycation index for monitoring fluctuating and poorly controlled type 2 diabetic patients
ACTA DIABETOLOGICA 48/2 :167-172,2011

Effects of leptin and adiponectin on pancreatic beta-cell function
METABOLISM-CLINICAL AND EXPERIMENTAL 60/ :1664-1672,2011

Apolipoprotein B/A1 ratio is associated with free androgen index and visceral adiposity and may be an indicator of metabolic syndrome in male children and adolescents
CLINICAL ENDOCRINOLOGY 74/5 :579-586,2011

Korean Red Ginseng (Panax ginseng) Improves Insulin Sensitivity in High Fat Fed Sprague-Dawley Rats
PHYTOTHERAPY RESEARCH 26/ :142-147,2012

A Simple Screening Score for Diabetes for the Korean Population Development, validation, and comparison with other scores
DIABETES CARE 35/8 :1723-1730,2012

Glycemic Effects of Once-a-Day Rapid-Acting Insulin Analogue Addition on a Basal Insulin Analogue in Korean Subjects with Poorly Controlled Type 2 Diabetes Mellitus
Diabetes and Metabolism Journal 36/3 :230-236,2012

Higher Morning to Evening Ratio in Total Dose of Twice-Daily Biphasic Insulin Analog Might Be Effective in Achieving Glucose Control in Patients with Poorly Controlled Type 2 Diabetes
DIABETES TECHNOLOGY & THERAPEUTICS 14/6 :508-514,2012

Aortic Calcification and Bone Metabolism: The Relationship between Aortic Calcification, BMD, Vertebral Fracture, 25-Hydroxyvitamin D, and Osteocalcin
CALCIFIED TISSUE INTERNATIONAL 91/6 :370-378,2012

Human Monoclonal Antibodies against Glucagon Receptor Improve Glucose Homeostasis by Suppression of Hepatic Glucose Output in Diet-Induced Obese Mice
PLOS ONE 7/12 :e50954-e50954,2012

Snail, a transcriptional regulator, represses adiponectin expression by directly binding to an E-box motif in the promoter
METABOLISM-CLINICAL AND EXPERIMENTAL 61/ :1622-1632,2012

Association of serum proprotein convertase subtilisin/kexin type 9 with carotid intima media thickness in hypertensive subjects.
METABOLISM-CLINICAL AND EXPERIMENTAL 62/6 :845-850,2013

Gastrectomy for Early Gastric Cancer is Associated with Decreased Cardiovascular Mortality in Association with Postsurgical Metabolic Changes
ANNALS OF SURGICAL ONCOLOGY 20/4 :1250-1257,2013

Additive association of vitamin D insufficiency and sarcopenia with low femoral bone mineral density in noninstitutionalized elderly population: the Korea National Health and Nutrition Examination Surveys 2009-2010
OSTEOPOROSIS INTERNATIONAL 24/ :2789-2799,2013

Transcription factor Snail is a novel regulator of adipocyte differentiation via inhibiting the expression of peroxisome proliferator?activated receptorγ
Cellular and Molecular Life Sciences 70/20 :3959-3971,2013

한국인에서 당뇨병 위험 예측 모델
The Journal of Korean Diabetes 14/ :6-10,2013

Comparison of association of glomerular filtration rate with metabolic syndrome in a community-based population using the CKD-EPI and MDRD study equations.
CLINICA CHIMICA ACTA 429/- :157-162,2014

Serum cholesterol concentration and prevalence, awareness, treatment, and control of high LDL cholesterol in the Korea National Health and Nutrition Examination Surveys 2008―2010: Beyond the tip of the iceberg
JOURNAL OF THE AMERICAN HEART ASSOCIATION 3/1 :446-,2014

The optimal morning: evening ratio in total dose of twice-daily biphasic insulin analogue in poorly controlled Type 2 diabetes: a 24-week multi-centre prospective, randomized controlled, open-labelled clinical study
DIABETIC MEDICINE 31/1 :68-75,2014

Screening for Prediabetes Using Machine Learning Models
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE /Article :1-8,2014

Early-stage chronic kidney disease, insulin resistance, and osteoporosis as risk factors of sarcopenia in aged population: The Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV), 2008-2009
OSTEOPOROSIS INTERNATIONAL 25/9 :2189-2198,2014

The combination of vitamin D deficiency and mild to moderate chronic kidney disease is associated with low bone mineral density and deteriorated femoral microarchitecture: Results from the knhanes 2008-2011
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 99/10 :3879-3888,2014

Inverse Association between Glycated Albumin and Insulin Secretory Function May Explain Higher Levels of Glycated Albumin in Subjects with Longer Duration of Diabetes.
PLOS ONE 9/Issue 9 :e108772-,2014

Non-Laboratory-Based Self-Assessment Screening Score for Non-Alcoholic Fatty Liver Disease: Development, Validation and Comparison with Other Scores
PLOS ONE 9/9 :1-10,2014

Postprandial C-peptide to glucose ratio as a predictor of beta-cell function and its usefulness for staged management of type 2 diabetes
JOURNAL OF DIABETES INVESTIGATION 5/5 :517-524,2014

비만, 인슐린 저항성과 비알코올성 지방간의 관계
The Journal of Korean Diabetes 15/ :76-81,2014

Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway
AUTOPHAGY 11/1 :46-59,2015

Risk of diabetes in patients treated with HMG-CoA reductase inhibitors
METABOLISM-CLINICAL AND EXPERIMENTAL 64/4 :482-488,2015

Glycated albumin and the risk of micro- and macrovascular complications in subjects with Type 1 Diabetes
CARDIOVASCULAR DIABETOLOGY 14/53 :1-8,2015

Comparing kidney outcomes in type 2 diabetes treated with different sulphonylureas in real-life clinical practice
DIABETES & METABOLISM 41/3 :208-215,2015

Central obesity is an independent risk factor for microalbuminuria in both the general Korean women and nondiabetic nonhypertensive subpopulation: Association of microalbuminuria and metabolic syndrome from the Korea National Health and Nutrition Ex
CLINICA CHIMICA ACTA -/488 :74-79,2015

Use of a Diabetes Self-Assessment Score to Predict Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis
MEDICINE 94/27 :e1103-,2015

Sarcopaenia is associated with NAFLD independently of obesity and insulin resistance: Nationwide surveys (KNHANES 2008?2011)
JOURNAL OF HEPATOLOGY 63/2 :486-493,2015

Undiagnosed diabetes is prevalent in younger adults and associated with a higher risk cardiometabolicprofilecomparedto diagnosed diabetes
AMERICAN HEART JOURNAL 170/4 :760-769,2015

Increased expression of ATP-binding cassette transporter A1 (ABCA1) as a possible mechanism for the protective effect of cilostazol against hepatic steatosis
METABOLISM-CLINICAL AND EXPERIMENTAL 64/11 :1444-1453,2015

Visceral adiposity is associated with altered myocardial glucose uptake measured by 18 FDG-PET in 346 subjects with normal glucose tolerance, prediabetes, and type 2 diabetes
CARDIOVASCULAR DIABETOLOGY 14/1 :148-148,2015

Association Between Heme Oxygenase-1 Promoter Polymorphisms and the Development of Albuminuria in Type 2 Diabetes: A Case?Control Study
MEDICINE 94/43 :e1825-,2015

Glycated Albumin Levels in Patients with Type 2 Diabetes Increase Relative to HbA(1c) with Time
BIOMED RESEARCH INTERNATIONAL 2015/Arti :1-8,2015

Dipeptidyl Peptidase-4 Inhibitor Alarms: Is Heart Failure Caused by a Class Effect?
Diabetes and Metabolism Journal 39/3 :204-206,2015

Performance of HbA(1c) for the prediction of diabetes in a rural community in Korea
DIABETIC MEDICINE 32/12 :1602-1610,2015

Cost-effectiveness analysis of low density lipoprotein cholesterollowering therapy in hypertensive patients with type 2 diabetes in Korea: single-pill regimen (amlodipine/atorvastatin) versus double-pill regimen (amlodipine + atorvastatin)
Epidemiology and Health 37/Articl :1-8,2015

Rosiglitazone Use and the Risk of Bladder Cancer in Patients With Type 2 Diabetes
MEDICINE 95/6 :e2786-,2016

Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK
INTERNATIONAL JOURNAL OF OBESITY 40/2 :356-365,2016

Sarcopenia Is Associated With Significant Liver Fibrosis Independently of Obesity and Insulin Resistance in Nonalcoholic Fatty Liver Disease: Nationwide Surveys (KNHANES 2008-2011)
HEPATOLOGY 63/3 :776-786,2016

Serum PTHrP predicts weight loss in cancer patients independent of hypercalcemia, inflammation, and tumor burden
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 101/3 :1207-1214,2016

Metformin restores parkin-mediated mitophagy, suppressed by cytosolic p53
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 17/122 :1-14,2016

Economic Burden of Hypoglycemia in Patients with Type 2 Diabetes Mellitus from Korea
PLOS ONE 11/3 :e0151282-,2016

Data Analytic Process of a Nationwide Population-Based Study Using National Health Information Database Established by National Health Insurance Service
Diabetes and Metabolism Journal 40/ :79-82,2016

자가항체 양성인 Ketosis-Prone 당뇨병 1예
The Journal of Korean Diabetes 17/1 :60-66,2016

저혈당과 의료 비용
The Journal of Korean Diabetes 17/1 :11-16,2016

How to Establish Clinical Prediction Models
대한내분비학회지 31/- :38-44,2016

Association between betatrophin/ANGPTL8 and non-alcoholic fatty liver disease: animal and human studies
SCIENTIFIC REPORTS 6/ :24013-,2016

Effects of Omega-3 Fatty Acid Supplementation on Diabetic Nephropathy Progression in Patients with Diabetes and Hypertriglyceridemia
PLOS ONE 11/5 :e0154683-,2016

Comparison and Validation of 10 Equations Including a Novel Method for Estimation of LDL-cholesterol in a 168,212 Asian Population
MEDICINE 95/14 :e3230-,2016

Urinary N-acetyl-β-D-glucosaminidase, an early marker of diabetic kidney disease, might reflect glucose excursion in patients with type 2 diabetes
MEDICINE 95/27 :e4114-,2016

Efficacy of different dipeptidyl peptidase-4 (DPP-4) inhibitors on metabolic parameters in patients with type 2 diabetes undergoing dialysis
MEDICINE 95/32 :e4543-,2016

Association between dietary acid load and the risk of cardiovascular disease: nationwide surveys (KNHANES 2008-2011)
CARDIOVASCULAR DIABETOLOGY 15/122 :1-14,2016

Sarcopenia is associated with albuminuria independently of hypertension and diabetes: (KNHANES 2008-2011)
METABOLISM-CLINICAL AND EXPERIMENTAL 65/10 :1531-1540,2016

Characteristics Predictive for a Successful Switch from Insulin Analogue Therapy to Oral Hypoglycemic Agents in Patients with Type 2 Diabetes
YONSEI MEDICAL JOURNAL 57/6 :1,395-1,403,2016

Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis
FREE RADICAL BIOLOGY AND MEDICINE 99/ :520-532,2016

Trends in Diabetes Incidence in the Last Decade Based on Korean National Health Insurance Claims Data
대한내분비학회지 31/2 :292-299,2016

A novel imaging platform for non-invasive screening of abnormal glucose tolerance
DIABETES RESEARCH AND CLINICAL PRACTICE 116/1 :83-85,2016

A genetic variant in GLP1R is associated with response to DPP-4 inhibitors in patients with type 2 diabetes
MEDICINE 95/44 :e5155-,2016

p62/SQSTM1 is required for the protection against endoplasmic reticulum stress-induced apoptotic cell death
FREE RADICAL RESEARCH 50/12 :1,408-1,421,2016

Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
대한내분비학회지 31/4 :598-603,2016

Lobeglitazone, a Novel Thiazolidinedione, Improves Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes: Its Efficacy and Predictive Factors Related to Responsiveness.
JOURNAL OF KOREAN MEDICAL SCIENCE 32/1 :60-69,2017

Morning Spot Urine Glucose-to-Creatinine Ratios Predict Overnight Urinary Glucose Excretion in Patients With Type 2 Diabetes.
ANNALS OF LABORATORY MEDICINE 37/1 :9-17,2017

Effect of statin on hepatocellular carcinoma in patients with type 2 diabetes: A nationwide nested case-control study
INTERNATIONAL JOURNAL OF CANCER 140/2 :798-806,2017

Differential association of body mass index on glycemic control in type 1 diabetes
DIABETES-METABOLISM RESEARCH AND REVIEWS 33/e2815 :1-8,2017

The renal tubular damage marker urinary N-acetyl-β-D-glucosaminidase may be more closely associated with early detection of atherosclerosis than the glomerular damage marker albuminuria in patients with type 2 diabetes.
CARDIOVASCULAR DIABETOLOGY 16/16 :1-11,2017

Association between Metformin Use and Risk of Lactic Acidosis or Elevated Lactate Concentration in Type 2 Diabetes
YONSEI MEDICAL JOURNAL 58/2 :312-318,2017

Increase in resting heart rate over 2 years predicts incidence of diabetes: A 10-year prospective study
DIABETES & METABOLISM 43/1 :25-32,2017

The hypertension drug, verapamil, activates Nrf2 by promoting p62-dependent autophagic Keap1 degradation and prevents acetaminophen-induced cytotoxicity
BMB REPORTS 50/2 :91-96,2017

Association between HbA1c and carotid atherosclerosis among elderly Koreans with normal fasting glucose
PLOS ONE 12/2 :e0171761-,2017

Metabolism-centric overview of the pathogenesis of Alzheimer’s disease.
YONSEI MEDICAL JOURNAL 58/3 :479-488,2017

Clinical parameters affecting dapagliflozin response in patients with type 2 dabetes
DIABETES & METABOLISM 43/2 :191-194,2017

Anatomic fat depots and cardiovascular risk: a focus on the leg fat using nationwide surveys (KNHANES 2008?2011)
CARDIOVASCULAR DIABETOLOGY 16/154 :1-11,2017

The Relationship between Increases in Morning Spot Urinary Glucose Excretion and Decreases in HbA1C in Patients with Type 2 Diabetes After Taking an SGLT2 Inhibitor: A Retrospective, Longitudinal Study7
DIABETES THERAPY 8/3 :601-609,2017

Diabetes self-assessment score and the development of diabetes A 10-year prospective study
MEDICINE 96/23 :e7067-,2017

Comparison between Atorvastatin and Rosuvastatin in Renal Function Decline among Patients with Diabetes
대한내분비학회지 32/2 :274-280,2017

BMI and All-Cause Mortality in Normoglycemia, Impaired Fasting Glucose, Newly Diagnosed Diabetes, and Prevalent Diabetes: A Cohort Study.
DIABETES CARE 40/8 :1,026-1,033,2017

Pre-sarcopenia is associated with renal hyperfiltration independent of obesity or insulin resistance: Nationwide Surveys (KNHANES 2008-2011)
MEDICINE 96/26 :e7165-,2017

Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated mediated activation of autophagy and NLRP3 inflammasome inhibition
AUTOPHAGY 13/10 :1,767-1,781,2017

임상 및 생화학적 지표에 기반한 비알코올성 지방간의 진단
The Journal of Korean Diabetes 18/2 :102-108,2017

Association between fasting glucose and all-cause mortality according to sex and age: A prospective cohort study
SCIENTIFIC REPORTS 7/1 :-,2017

Impact of diabetes mellitus and chronic liver disease on the incidence of dementia and all-cause mortality among patients with dementia
MEDICINE 96/47 :-,2017

Non-Alcoholic Fatty Liver Disease: The Emerging Burden in Cardiometabolic and Renal Diseases
Diabetes and Metabolism Journal 41/6 :430-437,2017

Association of non-alcoholic steatohepatitis with subclinical myocardial dysfunction in non-cirrhotic patients
JOURNAL OF HEPATOLOGY 68 /4 :764-772,2018

The association between skin auto-fluorescence of palmoplantar sites and microvascular complications in Asian patients with type 2 diabetes mellitus
SCIENTIFIC REPORTS 8/1 :6,309-6,315,2018

ApoB/ApoA-I ratio is independently associated with carotid atherosclerosis in type 2 diabetes mellitus with well-controlled LDL cholesterol levels
KOREAN JOURNAL OF INTERNAL MEDICINE 33/1 :138-147,2018

Color Doppler Ultrasonography Is a Useful Tool for Diagnosis of Peripheral Artery Disease in Type 2 Diabetes Mellitus Patients with Ankle-Brachial Index 0.91 to 1.40
Diabetes and Metabolism Journal 42/1 :63-73,2018

Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice
SCIENTIFIC REPORTS 8/1 :6,789-6,802,2018

Waist-to-calf circumstance ratio is an independent predictor of hepatic steatosis and fibrosis in patients with type 2 diabetes
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 33/5 :1,082-1,091,2018

Past and Current Status of Adult Type 2 Diabetes Mellitus Management in Korea: A National Health Insurance Service Database Analysis
Diabetes and Metabolism Journal 42/2 :93-100,2018

Effects of Serum Albumin, Calcium Levels, Cancer Stage and Performance Status on Weight Loss in Parathyroid Hormone-Related Peptide Positive or Negative Patients with Cancer
대한내분비학회지 33/1 :97-104,2018

Comparison of the Effects of Ezetimibe-Statin Combination Therapy on Major Adverse Cardiovascular Events in Patients with and without Diabetes: A Meta-Analysis
대한내분비학회지 33/2 :219-227,2018

Fasting serum amino acids concentration is associated with insulin resistance and pro-inflammatory cytokines
DIABETES RESEARCH AND CLINICAL PRACTICE 140/ :107-117,2018

Elevated urinary N-Acetyl-β-D-glucosaminidase is associated with high glycoalbumin-To-hemoglobin A1c ratio in type 1 diabetes patients with early diabetic kidney disease
SCIENTIFIC REPORTS 8/1 :6,710-6,718,2018

Differential association of ezetimibe-simvastatin combination with major adverse cardiovascular events in patients with or without diabetes: a retrospective propensity score-matched cohort study
SCIENTIFIC REPORTS 8/1 :11,925-11,932,2018

Elevated N-acetyl-beta-D-glucosaminidase, a urinary tubular damage marker, is a significant predictor of carotid artery atherosclerosis in type 1 diabetes, independent of albuminuria: A cross-sectional study
JOURNAL OF DIABETES AND ITS COMPLICATIONS 32/8 :777-783,2018

Sarcopenia is associated with the risk of significant liver fibrosis in metabolically unhealthy subjects with chronic hepatitis B
ALIMENTARY PHARMACOLOGY & THERAPEUTICS 48/3 :300-312,2018

Risk factors for hepatocellular carcinoma by age, sex, and liver disorder status: A prospective cohort study in Korea
CANCER 124/13 :2,748-2,757,2018

Fasting glucose and all-cause mortality by age in diabetes: A prospective cohort study
DIABETES CARE 41/3 :623-626,2018

Severe hypoglycemia is a risk factor for atrial fibrillation in type 2 diabetes mellitus: Nationwide population-based cohort study
JOURNAL OF DIABETES AND ITS COMPLICATIONS 32/2 :157-163,2018

Effects of lobeglitazone, a novel thiazolidinedione, on adipose tissue remodeling and brown and beige adipose tissue development in db/db mice
INTERNATIONAL JOURNAL OF OBESITY 42/3 :542-551,2018

Relationship between obstructive lung disease and non-alcoholic fatty liver disease in the Korean population: Korea National Health and Nutrition Examination Survey, 2007?2010
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE 13/ :2603-2611,2018

Combining SGLT2 Inhibition With a Thiazolidinedione Additively Attenuate the Very Early Phase of Diabetic Nephropathy Progression in Type 2 Diabetes Mellitus
Frontiers in Endocrinology 9/ :412-422,2018

Development and Validation of the Korean Diabetes Risk Score: A 10-Year National Cohort Study
Diabetes and Metabolism Journal 42/5 :402-414,2018

Efficacy and tolerability of novel triple combination therapy in drug-naive patients with type 2 diabetes from the TRIPLE-AXEL trial: protocol for an open-label randomised controlled trial
BMJ OPEN 8/9 :e022448-e022453,2018

Protective Effect of Metformin Against Thyroid Cancer Development: A Population-Based Study in Korea
THYROID 28/7 :864-870,2018

Clinical efficacy of the novel thiazolidinedione lobeglitazone in patients with type 2 diabetes
DIABETES & METABOLISM 44/5 :452-455,2018

Blood pressure level associated with lowest cardiovascular event in hypertensive diabetic patients.
JOURNAL OF HYPERTENSION 36/12 :2,434-2,443,2018

Relationship Between Circulating Netrin-1 Concentration, Impaired Fasting Glucose, and Newly Diagnosed Type 2 Diabetes
Frontiers in Endocrinology 9/ :691-698,2018

Clinical Evaluation of a Low-pain Long Microneedle for Subcutaneous Insulin Injection
BIOCHIP JOURNAL 12/4 :309-316,2018

Senescent T Cells Predict the Development of Hyperglycemia in Humans
DIABETES 68/ :156-162,2019

Sodium-glucose cotransporter 2 inhibitors regulate ketone body metabolism via inter-organ crosstalk
DIABETES OBESITY & METABOLISM 21/4 :801-811,2019

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