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Physician Directory

HOME > Hospitals > Severance Hospital > Departments > Endocrinology and Metabolism > Physician Directory

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Myungshik Lee
doctor's information
Name Myungshik Lee
Department
Major Metabolism, immunology
E-mail mslee0923@yuhs.ac
Homepage
Blog http://blog.iseverance.com/mslee0923

Research

IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: A key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death
JOURNAL OF IMMUNOLOGY 166/7 :4481-4489,2001

IFNg sensitizes ME-180 human cervical cancer cells to TNFa-induced apoptosis by inhibiting cytoprotective NF-kB activation
FEBS LETTERS 495/1-2 :66-70,2001

IFN gamma/TNF alpha synergism in MHC class II induction: effect of nicotinamide on MHC class II expression but not on islet-cell apoptosis
DIABETOLOGIA 45/3 :385-393,2002

Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis
ONCOGENE 21/20 :3139-3148,2002

Identification and functional characterization of a novel mutation of hepatocyte nuclear factor-1 alpha gene in a Korean family with MODY3
DIABETOLOGIA 46/5 :721-727,2003

Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes
DIABETOLOGIA 46/9 :1220-1227,2003

Resistance of mitochondrial DNA-depleted cells against cell death - Role of mitochondrial superoxide dismutase
JOURNAL OF BIOLOGICAL CHEMISTRY 279/9 :7512-7520,2004

Catecholamine cardiomyopathy associated with paraganglioma rescued by percutaneous cardiopulmonary support - Inverted takotsubo contractile pattern
CIRCULATION JOURNAL 71/12 :1993-1995,2007

NF-kappa B Activation in Hypothalamic Pro-opiomelanocortin Neurons Is Essential in Illness- and Leptin-induced Anorexia
The Journal of biological chemistry 285/13 :9706-9715,2010

Germline mutation of Glu70Lys is highly frequent in Korean patients with von Hippel-Lindau (VHL) disease
JOURNAL OF HUMAN GENETICS 59/9 :488-493,2014

Chronic HMGCR/HMG-CoA Reductase Inhibitor Treatment Contributes to Dysglycemia by Upregulating Hepatic Gluconeogenesis through Autophagy Induction.
AUTOPHAGY 11/11 :2089-2101,2015

Gut Microbiota and Metabolic Disorders
Diabetes and Metabolism Journal 39/3 :198-203,2015

FGF21 as a mediator of adaptive responses to stress and metabolic benefits of anti-diabetic drugs
JOURNAL OF ENDOCRINOLOGY 226/1 :R1-R16,2015

Age-dependent gait abnormalities in mice lacking the Rnf170 gene linked to human autosomal-dominant sensory ataxia
HUMAN MOLECULAR GENETICS 24/25 :7196-7206,2015

Effect of mitochondrial stress on the systemic metabolism
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 1350/- :61-65,2015

New mechanisms of metformin action: Focusing on mitochondria and the gut
JOURNAL OF DIABETES INVESTIGATION 6/6 :600-609,2015

CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis
SCIENTIFIC REPORTS 6/27938 :1-13,2016

Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis
AUTOPHAGY 12/8 :1,390-1,403,2016

Role of mitochondrial function in cell death and metabolism
FRONTIERS IN BIOSCIENCE-LANDMARK 21/ :1,233-1,244,2016

p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
NATURE COMMUNICATIONS 7/ :12,030-,2016

The orphan nuclear receptor erraγ regulates hepatic cb1 receptor-mediated fibroblast growth factor 21 gene expression
PLOS ONE 11/7 :e0159425-,2016

Secretagogin affects insulin secretion in pancreatic β-cells by regulating actin dynamics and focal adhesion.
BIOCHEMICAL JOURNAL 473/ :1,791-1,803,2016

Autophagy is a major regulator of beta cell insulin homeostasis
DIABETOLOGIA 59/ :1,480-1,491,2016

Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease
AUTOPHAGY 12/5 :784-800,2016

Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance
ARCHIVES OF PHARMACAL RESEARCH 39/99 :1503-1518,2016

Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated mediated activation of autophagy and NLRP3 inflammasome inhibition
AUTOPHAGY 13/10 :1,767-1,781,2017

Alterations in gut microbiota and immunity by dietary fat
YONSEI MEDICAL JOURNAL 58/6 :1,083-1,091,2017

Obesogenic diet-induced gut barrier dysfunction and pathobiont expansion aggravate experimental colitis
PLOS ONE 12/11 :e0187515-,2017

A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes.
NATURE COMMUNICATIONS 9/1 :1,438-,2018

Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice
SCIENTIFIC REPORTS 8/1 :6,789-6,802,2018

The Role of Autophagy in Systemic Metabolism and Human-Type Diabetes
MOLECULES AND CELLS 41/1 :11-17,2018

Pathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic Approaches
Frontiers in Endocrinology 9/ :485-499,2018

Nonsynonymous Variants in PAX4 and GLP1R Are Associated With Type 2 Diabetes in an East Asian Population
DIABETES 67/9 :1,892-1,902,2018

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