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Physician Directory

HOME > Hospitals > Severance Hospital > Departments > Neurosurgery > Physician Directory

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Seok-Gu Kang
doctor's information
Name Seok-Gu Kang
Department
Major Neurosurgery/ Brain Tumor, Neuro-oncology, Head Trauma
E-mail SEOKGU9@YUHS.AC
Homepage
Blog http://blog.iseverance.com/seokgu9

Research

C-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in glioma stem-like cells
ONCOGENE 31/44 :4655-4666,2012

Isolation of glioma cancer stem cells in relation to histological grades in glioma specimens.
CHILDS NERVOUS SYSTEM 29/2 :217-229,2013

Postoperative nasal symptoms associated with an endoscopic endonasal transsphenoidal approach
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY 270/4 :1355-1359,2013

Changes in the biological characteristics of glioma cancer stem cells after serial in vivo subtransplantation.
CHILDS NERVOUS SYSTEM 29/1 :55-64,2013

Existence of glioma stroma mesenchymal stemlike cells in Korean glioma specimens
CHILDS NERVOUS SYSTEM 29/4 :549-563,2013

Increased in vivo angiogenic effect of glioma stromal mesenchymal stem-like cells on glioma cancer stem cells from patients with glioblastoma
INTERNATIONAL JOURNAL OF ONCOLOGY 42/5 :1754-1762,2013

A novel 2-pyrone derivative, BHP, impedes oncogenic KRAS-driven malignant progression in breast cancer
CANCER LETTERS 337/1 :49-57,2013

Isolation of mesenchymal stem-like cells in meningioma specimens
INTERNATIONAL JOURNAL OF ONCOLOGY 43/4 :1260-1268,2013

Bilateral Nasoseptal Flaps for Endoscopic Endonasal Transsphenoidal Approach
JOURNAL OF CRANIOFACIAL SURGERY 24/ :1569-1572,2013

Fractionated radiation-induced nitric oxide promotes expansion of glioma stem-like cells
CANCER SCIENCE 104/ :1172-1177,2013

Isolation of tumor spheres and mesenchymal stem-like cells from a single primitive neuroectodermal tumor specimen
CHILDS NERVOUS SYSTEM 29/12 :2229-2239,2013

Bilateral modified nasoseptal "rescue" flaps in the endoscopic endonasal transsphenoidal approach
LARYNGOSCOPE 123/11 :2605-2609,2013

Isolation of Mesenchymal Stem-like Cells from a Pituitary Adenoma Specimen
대한의생명과학회지 19/4 :295-302,2013

Temozolomide salvage chemotherapy for recurrent anaplastic oligodendroglioma and oligo-astrocytoma
JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 54/6 :489-495,2013

Study of freshly excised brain tissues using terahertz imaging
BIOMEDICAL OPTICS EXPRESS 5/8 :2837-2842,2014

Role of the superior turbinate when performing endoscopic endonasal transsphenoidal approach
FOLIA MORPHOLOGICA 73/1 :73-78,2014

Prognostic value of glioma cancer stem cell isolation in survival of primary glioblastoma patients
STEM CELLS INTERNATIONAL 2014/0 :0-0,2014

Atypical location and clinical behavior of a subset of intracranial germ cell tumors in children younger than 3 years of age
JOURNAL OF NEUROSURGERY-PEDIATRICS 14/4 :348-355,2014

Potential use of glioblastoma tumorsphere: Clinical credentialing
ARCHIVES OF PHARMACAL RESEARCH 38/3 :402-407,2015

T2 - and T*2-weighted MRI of rat glioma using polysorbate-coated magnetic nanocrystals as a blood-pool contrast agent
RSC ADVANCES 5/25 :19708-19714,2015

Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy
NATURE MEDICINE 21/4 :395-400,2015

Primary diffuse leptomeningeal gliosarcoma
Brain Tumor Reserach and Treatment 3/1 :34-38,2015

The Added Prognostic Value of Preoperative Dynamic Contrast-Enhanced MRI Histogram Analysis in Patients with Glioblastoma: Analysis of Overall and Progression-Free Survival
AMERICAN JOURNAL OF NEURORADIOLOGY 36/12 :2235-2241,2015

Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway
STEM CELLS 33/8 :2400-2415,2015

Pseudoprogression in glioblastoma patients: the impact of extent of resection
JOURNAL OF NEURO-ONCOLOGY 126/3 :559-566,2016

Tumor mesenchymal stem-like cell as a prognostic marker in primary glioblastoma
STEM CELLS INTERNATIONAL 2016/Arti :1-7,2016

PKCδ activated by c-MET enhances infiltration of human glioblastoma cells through NOTCH2 signaling
ONCOTARGET 7/4 :4890-4902,2016

Strategies of mesenchymal invasion of patient-derived brain tumors: Microenvironmental adaptation.
SCIENTIFIC REPORTS 25/6 :24912-24912,2016

Current and future perspectives in craniosynostosis.
JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 59/3 :247-249,2016

Failure of a patient-derived xenograft for brain tumor model prepared by implantation of tissue fragments
CANCER CELL INTERNATIONAL 16/43 :1-6,2016

Isolation and characterization of tumorspheres from a recurrent pineoblastoma patient: Feasibility of a patient-derived xenograft.
INTERNATIONAL JOURNAL OF ONCOLOGY 49/ :567-578,2016

Histopathological implications of ventricle wall 5-aminolevulinic acid-induced fluorescence in the absence of tumor involvement on magnetic resonance images
ONCOLOGY REPORTS 36/2 :837-844,2016

A polyethylene glycol-based hydrogel as macroporous scaffold for tumorsphere formation of glioblastoma multiforme
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY 39/ :10-15,2016

Incremental Prognostic Value of ADC Histogram Analysis over MGMT Promoter Methylation Status in Patients with Glioblastoma
RADIOLOGY 281/1 :175-184,2016

Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A)
ONCOTARGET 7/40 :65,643-65,659,2016

Terahertz reflectometry imaging for low and high grade gliomas
SCIENTIFIC REPORTS 6/36,040 :1-9,2016

Success of tumorsphere isolation from WHO grade IV gliomas does not correlate with the weight of fresh tumor specimens: an immunohistochemical characterization of tumorsphere differentiation
CANCER CELL INTERNATIONAL 16/75 :1-7,2016

Hemangiopericytomas in the Central Nervous System: A Multicenter Study of Korean Cases with Validation of the Usage of STAT6 Immunohistochemistry for Diagnosis of Disease
ANNALS OF SURGICAL ONCOLOGY 23/ :S954-S961,2016

Tumor-associated mesenchymal stem-like cells provide extracellular signaling cue for invasiveness of glioblastoma cells
ONCOTARGET 8/1 :1,438-1,448,2017

Concurrent Chemoradiotherapy with Temozolomide Followed by Adjuvant Temozolomide for Newly Diagnosed Glioblastoma Patients: A Retrospective Multicenter Observation Study in Korea
CANCER RESEARCH AND TREATMENT 49/1 :193-203,2017

Inhibition of glioblastoma tumorspheres by combined treatment with 2-deoxyglucose and metformin
NEURO-ONCOLOGY 19/2 :197-207,2017

Primary central nervous system lymphoma and atypical glioblastoma: differentiation using the initial area under the curve derived from dynamic contrast-enhanced MR and the apparent diffusion coefficient
EUROPEAN RADIOLOGY 27/4 :1,344-1,351,2017

Professional Experience

Surgical Neuro-Oncology
Glioma
Metastatic brain tumor
Meningioma
Translational research for brain tumor.

Membership

Society for Neuro-Oncology
Europian Association for Neuro-Oncology
Korean Neurosurgical Society
Korean Society for Neuro-Oncology
Korean Brain Tumor Society
International Society for Pediatric Neurosurgery
Korean Society for Pediatric Neurosurgery
Korean Society of Pediatric Neuro-Oncology

Academic Career

Internship : 1995-1996, St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.
Residency : 1996-2000, Neurosurgery, St. Mary's Hospital, The Catholic University of Korea Colleage of Medicine, Seoul, Korea.
Military service: 2000-2001, The Armed Forced Gangnung Hospital (Captain)
2001-2003, Medical Bureau, Presidential Security Service (Captain)
Fellowship : 2003-2004 Neurosurgery (Brain tumor), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
2004-2005 Neurosurgery (Pediatric Neurosurgery), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
2007-2009 Post-doc fellow, Brain Tumor Center, Neurosurgery, M. D. Anderson Cancer Center, Houston, Texas, USA
Academic Appointments
: March, 2005 Assistant professor of Neurosurgery, The Catholic University of Korea College of Medicine, Uijeongbu St. Mary's Hospital, Uijeongbu, Korea
: April/2009 Associate professor of Neurosurgery, The Catholic University of Korea College of Medicine, Uijeongbu St. Mary's Hospital, Uijeongbu, Korea
: March/2010 Associate professor of Neurosurgery, The Catholic University of Korea College of Medicine, Seoul St. Mary's Hospital, Seoul, Korea

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